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SPIN is currently conducting a study on "Current practice of phototherapy in psoriasis: a worldwide survey among dermatologists".
Phototherapy is one the most commonly used systemic therapies for psoriasis. Despite its widespread use in psoriasis therapy, dermatologists’ practice regarding the use of phototherapy has not been investigated on global scale. As such, the main objective of this study is to evaluate the real life use of phototherapy for psoriasis treatment in the dermatological community worldwide.
This project is led by Lajos Kemeny and Rolland Gyulai (Hungary) on behalf of SPIN, with the help of a steering committee including Luigi Naldi (Italy), José Manuel Carrascosa (Spain), Nejib Doss (Tunisia), Peter van de Kerkhof (The Netherlands) and Adrian Tanew (Austria).
A worldwide survey is being carried in 2016-2017. We will keep you updated!
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Latin American Clinical Practice Guidelines on the Systemic Treatment of Psoriasis
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Recent publications on Psoriasis and Atopic Dermatitis
on Psoriasis
Mimicking cigarette smoke exposure to assess cutaneous toxicity.
Prieux R et al.
Mimicking cigarette smoke exposure to assess cutaneous toxicity.
Toxicol In Vitro.
2020 Feb , 62:104664.
Cigarette smoke stands among the most toxic environmental pollutants and is composed of thousands of chemicals including polycyclic aromatic hydrocarbons (PAHs). Despite restrict cigarette smoking ban in indoor or some outdoor locations, the risk of non-smokers to be exposed to environmental cigarette smoke is not yet eliminated. Beside the well-known effects of cigarette smoke to the respiratory and cardiovascular systems, a growing literature has shown during the last 3 decades its (...)
see on pubmed
Penta-O-galloyl-β-D-glucose from Paeonia lactiflora Pall. root extract enhances the expression of skin barrier genes via EGR3.
J Ethnopharmacol.
2020 Feb 10, 248:112337.
Paeonia lactiflora Pall. has long been used to treat inflammatory skin diseases, such as psoriasis.
see on pubmed
CARD14/CARMA2sh and TANK differentially regulate poly(I:C)-induced inflammatory reaction in keratinocytes.
J. Cell. Physiol..
2020 Mar , 235, (3):1895-1902.
CARD14/CARMA2sh (CARMA2sh) is a scaffold protein whose mutations are associated with the onset of human genetic psoriasis and other inflammatory skin disorders. Here we show that the immunomodulatory adapter protein TRAF family member-associated NF-κB activator (TANK) forms a complex with CARMA2sh and MALT1 in a human keratinocytic cell line. We also show that CARMA2 and TANK are individually required to activate the nuclear factor κB (NF-κB) response following exposure to (...)
see on pubmed
on Atopic Dermatitis
Mimicking cigarette smoke exposure to assess cutaneous toxicity.
Prieux R et al.
Mimicking cigarette smoke exposure to assess cutaneous toxicity.
Toxicol In Vitro.
2020 Feb , 62:104664.
Cigarette smoke stands among the most toxic environmental pollutants and is composed of thousands of chemicals including polycyclic aromatic hydrocarbons (PAHs). Despite restrict cigarette smoking ban in indoor or some outdoor locations, the risk of non-smokers to be exposed to environmental cigarette smoke is not yet eliminated. Beside the well-known effects of cigarette smoke to the respiratory and cardiovascular systems, a growing literature has shown during the last 3 decades its (...)
see on pubmed
Sublingual Immunotherapy for Other Indications: Venom Large Local, Latex, Atopic Dermatitis, and Food.
Immunol Allergy Clin North Am.
2020 Feb , 40, (1):41-57.
There is some evidence to support the use of sublingual immunotherapy (SLIT) in food allergy, although its role is unclear. One randomized, double-blind, placebo-controlled trial supports the safe and efficacious use of dust mite SLIT in children with mild to moderate atopic dermatitis, but these data have not been confirmed. Although there are several randomized, double-blind, placebo-controlled trials to support the use of SLIT-LATEX, this product is not available in the United States and (...)
see on pubmed
The Cost-Effectiveness of Allergen Immunotherapy Compared with Pharmacotherapy for Treatment of Allergic Rhinitis and Asthma.
Immunol Allergy Clin North Am.
2020 Feb , 40, (1):69-85.
This article evaluates the cost-effectiveness of allergy immunotherapy (AIT) in the treatment of allergic rhinitis, asthma, and other allergic conditions. An extensive search of the PubMed and Medline databases (up to December 2018) was conducted. There is strong evidence in the collective literature, which included individual studies and systematic reviews, that AIT is cost-effective in the management of allergic rhinitis and asthma as compared with standard drug treatment alone. The (...)
see on pubmed
