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News from the web office
- 2017/06/05 PIN becomes SPIN - Skin Inflammation & Psoriasis International Network
- 2016/10/29 PSO 2016 Congress - Webcasts Available!
- 2016/05/26 PIN Survey on Phototherapy
- 2016/02/20 PIN Study on Therapeutic Patient Education
- 2016/02/19 World Directory of Psoriasis Medical Resources - February 2016 Update
- 2015/10/22 World Directory of Psoriasis Medical Resources - October 2015 Update
- 2015/10/22 PIN Survey on Therapeutic Patient Education
- 2015/03/30 World Directory of Psoriasis Medical Resources - March 2015 Update
- 2014/10/29 World Directory of Psoriasis Medical Resources
- 2014/05/22 New President of PIN’s Scientific Committee
- 2014/05/22 World Listing of Psoriasis Medical Resources for Patients
- 2014/05/22 Results of PIN’s Methotrexate Survey Published
- 2013/10/29 Update of PIN National Representatives!
- 2013/10/25 New members join PIN Committee!
- 2013/10/25 Results of Worldwide Methotrexate Study
- 2013/05/28 Survey on Psoriasis Services Available Worldwide
- 2013/04/11 PSO 2013 Congress - what’s new?
- 2012/10/29 Psoriasis International Network Committee
- 2012/10/26 PSO 2013 Congress: Call For Abstracts
- 2012/10/25 Like us on Facebook!
- 2012/06/08 Worldwide Methotrexate Survey
- 2012/06/08 PSO 2013 Congress website is open!
- 2012/01/02 Survey of Psoriasis International Network: Where are we at?
- 2011/04/12 1st Report on Psoriasis International Network Survey
- 2011/02/01 New websites for Iran and Syria!
- 2010/10/29 New developments in the Asia-Pacific Region
- 2010/10/29 Special Focus On - PSORIASIS 2010: 3rd International Congress on Psoriasis
- 2010/10/19 Launch of Latin American Journal of Psoriasis and Psoriatic Arthritis - November 2010
- 2009/11/27 Psychology and psoriasis: A new intervention for psoriasis patients
- 2009/07/08 Psoriasis 2010 - "Congress of the Psoriasis International Network"
- 2009/06/16 Participate in Transparency Policy Consultation by European Medecines Agency
- 2009/03/06 Development of Psoriasis International Homepage
- 2009/01/27 Psoriasis 2010 - Congress of the Psoriasis International Network
- 2008/11/20 Research article released on the health care and needs of Italian psoriasis patients
- 2008/08/04 New book on the history of Psoriasis released!
- 2008/07/29 Consensus & Controversies is now online!
- 2007/12/09 IMPORTANT
- 2007/12/09 www.psoriasis-international.org!
Events
- 2019/04/18 SPIN Congress 2019 in Paris coming soon
- 2018/07/16 SPIN Symposium at the Spring continental meeting - Tehran, 25-27 April 2018
- 2018/02/22 2nd National Meeting of the Egyptian Society for Psoriasis
- 2018/02/21 1st Psoriasis Symposium - Sarajevo 2017
- 2017/06/28 15th São Paulo Meeting of Psoriasis and Vitiligo
- 2017/06/21 SPIN 2019 Congress
- 2017/04/20 1st Psoriasis Symposium of the psoriais association of Bosnia and Herzegovina!
- 2017/02/01 1st National Meeting of the Egyptian Society for Psoriasis
- 2016/10/29 World Psoriasis Day 2016 - Breaking Barriers
- 2016/05/26 PSO 2016 Congress - Update your knowledge!
- 2016/05/26 Psoriasis Shout Out Awareness Dance
- 2016/02/24 PSO 2016 Congress - Scholarship Programme
- 2016/02/23 WHO publishes Global Report on Psoriasis
- 2016/02/05 1st Psoriasis Seminar in Iran
- 2015/11/23 5th Psoriasis Interdisciplinary Congress in Lithuania
- 2015/11/23 Observation of World Psoriasis Day 2015 by Indian Society of Teledermatology
- 2015/10/29 World Psoriasis Day 2015 - IFPA Press Release
- 2015/10/29 Psoriasis Shout Out® films
- 2015/10/28 4th World Psoriasis & Psoriatic Arthritis Conference - Brief Report
- 2015/10/22 PSO 2016 Congress - Website open and running!
- 2015/10/06 9th Annual Scientific Meeting of the French Psoriasis Research Group
- 2015/03/30 4th World Psoriasis & Psoriatic Arthritis Conference
- 2015/03/19 International Dermatology Patient Organization Conference
- 2015/03/19 International Congress "PSOFUTURE New directions from the Eternal City"
- 2014/12/02 World Psoriasis Day - Swimmer’s Night: Great success in Hungary
- 2014/11/28 Swim for psoriasis: an EADV initiative for the World Psoriasis Day
- 2014/11/26 PIN Symposium at 2nd Latin American Congress of Psoriasis
- 2014/11/21 4th World Psoriasis & Psoriatic Arthritis Conference
- 2014/11/20 Indian Society of Teledermatology observes World Psoriasis Day - 2014
- 2014/10/28 World Psoriasis Day 2014
- 2014/07/10 PIN Symposium at EADV Congress in Amsterdam
- 2014/07/08 2nd Latin American Congress of Psoriasis
- 2013/10/29 World Psoriasis Day 2013
- 2013/10/25 SPECIAL FOCUS ON "PSO 2013 CONGRESS"
- 2013/06/21 PSO 2013 Congress - Last Days to Register
- 2013/05/28 PIN Symposium at EADV Congress in Istambul
- 2013/04/11 International Psoriasis Council Events 2013
- 2013/04/02 Final Report of 1st Latin American Congress of Psoriasis
- 2013/01/28 2nd PIN Symposium at PALD Meeting
- 2013/01/14 World Psoriasis Day 2012 - Special "Focus On"
- 2012/10/29 World Psoriasis Day 2012
- 2012/09/12 VII Course on Immunologic / Biologic Therapy in Dermatology
- 2012/06/08 1st PIN Symposium at 1st Latin American Congress of Psoriasis
- 2012/03/22 1st Latin American Congress of Psoriasis
- 2012/01/20 Call for Abstracts - 3rd World Psoriasis & Psoriatic Arthritis Conference 2012
- 2012/01/02 World Psoriasis Day 2011 - Special "Focus On"
- 2011/11/15 3rd World Psoriasis & Psoriatic Arthritis Conference 2012
- 2011/10/29 World Psoriasis Day 2011
- 2011/03/10 Special Focus On - World Psoriasis Day 2010
- 2011/01/25 World Psoriasis Day - Argentina Report 2010
- 2011/01/05 کنگره بین المللی درماتولوژی
- 2010/11/09 World Psoriasis Day in Croatia
- 2010/10/31 1st World Psoriasis Day in Lebanon!
- 2010/10/29 WORLD PSORIASIS DAY 2010
- 2010/09/14 IFPA Satellite Symposium at the 19th Congress of the EADV
- 2010/09/13 4th Symposium of the French Psoriasis Group
- 2010/06/18 A FORUM of HOPE, the Philippines’ National Psoriasis and Psoriatic Arthritis Conference 2010
- 2010/03/30 3rd Latin American Psoriasis Meeting - SOLAPSO
- 2010/03/30 World Psoriasis Day 2009 - Official Report
- 2009/12/08 World Psoriasis Day in Poland
- 2009/10/29 World Psoriasis Day 2009
- 2009/10/16 VI National Mexican Psoriasis Congress
- 2009/10/16 Philippines’ FunWalk@Baywalk- World Psoriasis Day
- 2009/09/10 Psoriasis Day in University of Buenos Aires
- 2009/09/10 Psoriasis Group in Israel organises course - ’’The Art of Treating Psoriasis’’
- 2009/05/05 3rd Symposium of the French Psoriasis Group
- 2009/04/24 XIII Jornadas Psoriasis 2009 - Spain
- 2009/04/15 First Latin American Meeting of Psoriasis
- 2009/02/16 2nd World Psoriasis and Psoriatic Arthritis Conference
- 2008/10/22 PSOPortugal World Psoriasis Day celebrations
- 2008/09/29 National Psoriasis and Psoriatic Arthritis Conference (NPPAC) - Philippines
- 2008/08/28 CROATIAN-ITALIAN SYMPOSIUM ON PSORIASIS
- 2008/08/04 Planned activities for World Psoriasis Day 2008 in Czech Republic
- 2008/07/31 Second Scientific Meeting of the French Psoriasis Group
- 2008/06/25 5th International Congress "Psoriasis - From Gene to Clinic"
- 2008/06/16 “XIIIth COSMODERM – Joint Meeting of ESCAD and the Hellenic Society of Dermatology and Venereology”
- 2007/12/09 www.psoriasis-international.org!
- 2007/12/09 World Psoriasis Day 29 October
News from medical groups
- 2018/04/18 3rd Turkish National Psoriasis Symposium
- 2017/06/21 Brazilian Center for Psoriasis Studies joins SPIN!
- 2017/06/21 Costa Rica Psoriasis Group - Meet them!
- 2017/02/02 Works of the 1st Senegalese Psoriasis Day published!
- 2016/07/29 Swiss S1 Guidelines for Systemic treatment of psoriasis vulgaris
- 2016/05/26 Egyptian Psoriasis Conference in Alexandria
- 2016/02/05 Psoriasis Group in Bosnia and Herzegovina joins PIN!
- 2016/02/05 1st Psoriasis Seminar in Iran
- 2015/11/23 5th Psoriasis Interdisciplinary Congress in Lithuania
- 2015/11/23 Observation of World Psoriasis Day 2015 by Indian Society of Teledermatology
- 2015/07/24 Psoriasis Day Out - Tanta Psoriasis Clinic Egypt
- 2015/06/24 International Dermatology Outcome Measures Group (IDEOM)
- 2015/03/19 Arab Psoriasis Network Session at Sharm Derma 2014
- 2014/11/20 COLOMBIAN EVIDENCE BASED GUIDELINES FOR PSORIASIS
- 2014/11/04 Arab Psoriasis Network at EADV Amsterdam
- 2014/07/08 Psoriasis Day in Tanta - Egypt
- 2014/05/22 1st Senegalese Psoriasis Days
- 2014/05/22 Update on Psoriasis epidemiology in Spain
- 2014/05/22 1st National Psoriasis Symposium in Turkey
- 2013/10/08 Creation of the Arab Psoriasis Network!
- 2013/10/08 Research project on the use of fumaric acid esters and hydroxy-urea
- 2013/04/03 Upcoming Launch of West African Psoriasis Group
- 2013/04/02 Update from the Malaysian Psoriasis Registry
- 2013/04/02 Setting up a psoriasis outpatient clinic in Tanta - Egypt
- 2013/01/13 Turkey founds National Psoriasis Society!
- 2013/01/13 New Colombian Guidelines for Psoriasis!
- 2012/12/10 Launch of Egyptian Psoriasis Network
- 2012/10/26 Programme of the 6th Meeting of the French Psoriasis Research Group
- 2012/10/26 Colombian Group of Psoriasis and Psoriatic Arthritis (ColPsor)
- 2012/09/11 SKIN IN PSYCHOANALYSIS by Jorge C. Ulnik
- 2012/07/02 Patient focused decision aid tool for psoriasis
- 2012/06/02 Update of the Chinese Psoriasis Network
- 2012/03/28 Report of the 5th Symposium of the French Psoriasis Research Group
- 2012/03/22 GRAPPA - Group for Research and Assessment of Psoriasis and Psoriatic Arthritis
- 2012/01/02 Psoriasis in Croatia
- 2011/11/16 Symposium of Psoriasis and Pshycodermatology - SOLAPSO
- 2011/11/14 Starting my Psoriasis Outpatient Clinic
- 2011/05/03 Ukrainian Psoriasis Association - a connecting link between patient and doctor
- 2011/04/12 Malaysian Psoriasis Registry on Psoriasis International Network
- 2010/11/17 Psoriasis Association of Georgia - World Psoriasis Day 2010
- 2010/11/15 PSO Georgia joins Psoriasis International Network
- 2010/10/31 Main activities of the Portuguese Society of Dermatology for WPD 2010
- 2010/07/12 3rd Latin American Meeting on Psoriasis
- 2010/06/29 14th Annual meeting of The Korean Society for Psoriasis
- 2010/06/18 "First Kyiv Dermatological days"
- 2010/05/25 Psoriasis - Israel
- 2010/04/22 Formation of the Grid of Psoriasis Forum India
- 2010/03/30 The Jordanian Society for Dermatology and Venereology joins Psoriasis International Network
- 2009/11/25 3rd Symposium of the French Psoriasis Group
- 2009/11/16 Algerian Psoriasis Group - Record of the Year 2009
- 2009/11/10 Activities on Psoriasis in 2009 – the Division of Evidence based Medicine in Dermatology (Berlin / Germany)
- 2009/10/28 The Libyan Society of Dermatologists joins Psoriasis International Network
- 2009/10/01 Health Services Research in Psoriasis – The German Approach
- 2009/09/24 Example of collaboration between dermatologists and patient associations: an Italian study
- 2009/09/23 Tunisian Study on Anti-MCV in Psoriasis
- 2009/09/10 Psoriasis Medical Group created in Turkey
- 2009/07/07 Consensus Documents of the Spanish Psoriasis Group
- 2009/04/15 SOLAPSO – Sociedad Latinoamericana de Psoriasis
- 2009/03/27 Algeria creates Psoriasis Group and joins Psoriasis International
- 2009/03/16 Indonesian Psoriasis Study Group joins the Psoriasis International Network
- 2009/03/05 Suspension of Market Authorisation of Raptiva
- 2009/03/05 French Psoriasis Group renews its Scientific Board
- 2009/01/09 Psoriasis in Tunisia: Genetic Study
- 2009/01/06 Psoriasis Forum Hyderabad-India
- 2008/12/16 4th Croatian-Italian Symposium on Psoriasis
- 2008/12/04 The Latin America Psoriasis Society (SOLAPSO) is now linked with Psoriasis-international.org
- 2008/11/26 The Chinese Dermatologist Association joins Psoriasis International
- 2008/11/26 Moldova in the Psoriasis International Network
- 2008/11/25 Psoriasis sessions in the 8th Asian Dermatological Congress
- 2008/11/24 2nd Symposium of the French Psoriasis Group
- 2008/11/24 Psocare Italy: recent activities
- 2008/10/28 Japanese Society for Psoriasis Research
- 2008/10/24 Psoriasis India Forum now on Psoriasis International Network
- 2008/10/14 Epidemio-clinical features of psoriasis in Tunisia through a multicentre study
- 2008/09/25 The Psoriasis Group of the Bulgarian Dermatological Society is now on Psoriasis International
- 2008/09/15 Deutsche Psoriasis Leitlinien Gruppe, a new reference in Psoriasis-International.org
- 2008/09/04 Tunisia Psoriasis Club in the Psoriasis International Network
- 2008/08/28 Psoriasis in Papers Published in Egypt
- 2008/08/28 The Psoriasis Club of Szeged now member of the Psoriasis International Network
- 2008/08/28 The Syrian Society of Dermatology, Venereology and Psoriasis joins Psoriasis International
- 2008/07/11 Japan, newest country in the Psoriasis International Network
- 2008/07/10 FIRST HUNGARIAN NATIONAL PSORIASIS CONVENTION AND OPEN DAY
- 2008/07/04 The Psoriasis Society of Israel - new member of Psoriasis International Network!
- 2008/07/04 THE PSOCARE PROJECT IN ITALY 2005-2007
- 2008/06/10 Saudi Arabia, new partner country of the Psoriasis International Network
- 2008/06/10 The Nigerian Association of Dermatologists (NAD), new member of Psoriasis International
- 2008/06/10 DERMATOMAROC linked with Psoriasis-international.org!
- 2008/06/10 German Psoriasis Group
- 2008/05/29 Psocare, the Italian psoriasis network joins Psoriasis International
- 2008/05/26 The Taiwanese Dermatological Association joins the Psoriasis International network
- 2008/05/19 The Croatian Psoriasis Working Group’s website is now available!
- 2008/04/23 New member countries of Psoriasis International: Croatia, Egypt and Iran
- 2008/01/30 The Spanish Psoriasis Group of the Spanish Academy of Dermatology and Venereology joins Psoriasis International
- 2007/12/10 The "French Group of Psoriasis" launches its Website
News from patients associations
- 2017/02/08 France Psoriasis - 2016 World Psoriasis Day
- 2016/05/26 Senegal Patients Association joins PIN!
- 2015/08/04 Epidermia Greece: a new partner association of PIN
- 2015/08/01 Canadian Association of Psoriasis Patients joins PIN!
- 2015/04/09 AEPSO Argentina launches digital map to find people with psoriasis in the country
- 2015/03/30 A global call for awareness of psoriasis as a disability
- 2014/07/08 WHO approves Psoriasis Resolution!
- 2014/05/22 EUROPSO Youth Round Table
- 2013/10/25 Bulgarian patient association joins PIN!
- 2013/10/08 WHO resolution on psoriasis!
- 2013/05/22 Croatian Psoriasis Association joins Psoriasis International Network!
- 2013/04/02 PsorAsia launches PsorCARE programme in Singapore
- 2013/01/05 Spanish psoriasis patient wins 2012 Under the Spotlight Award
- 2012/10/26 EUROPSO: Psoriasis Mandate Petition
- 2012/10/12 Psoriasis Philippines’ Update - October 2012
- 2012/07/02 ADIPSO’s VII International Congress Psoriasis: A medical and social problem
- 2012/06/01 News from Russia’s Patient Association "INTERACTION"
- 2012/05/24 4th Meeting of LATINAPSO Patient Associations Network
- 2012/02/29 Patient association from Russia joins Psoriasis International Network!
- 2011/11/18 Update EUROPSO activities
- 2011/11/15 New IFPA websites launched!
- 2011/11/14 IFPA attends United Nations High-level Meeting on Noncommunicable Diseases
- 2011/09/10 VII Association Meeting Psoriasis - Mexico
- 2011/07/26 3rd Yearly Meeting of LATINAPSO
- 2011/05/30 Chinese Taipei: Psoriasis Association in Taiwan
- 2011/03/13 Georgian Psoriasis Patients’ Association joins Psoriasis International Network
- 2011/01/25 A year of LATINAPSO
- 2010/11/13 Activities Accion Psoriasis (Spain) on World Psoriasis Day
- 2010/10/29 THE EUROPSO PSORIASIS PATIENT STUDY
- 2010/06/29 2nd LATINAPSO Meeting
- 2010/06/18 1st Psoriasis Patients Meeting in Chile
- 2010/06/17 Mexican Patient Association Activities 2010
- 2010/04/22 Psoriasis Caravan in Philippines
- 2010/04/14 Ukrainian Psoriasis Association now on Psoriasis International Network!
- 2009/11/27 Chilean Psoriasis Corporation now linked to Psoriasis-international.org
- 2009/11/27 Africa Psoriasis Organization (Kenya) joins Psoriasis International Network
- 2009/11/10 1st Meeting of LATINAPSO - Latin American Psoriasis Network
- 2009/09/18 2nd World Psoriasis and Psoriatic Arthritis Conference 2009
- 2009/09/17 "Vitamin D - The vitamin of the sun"
- 2009/07/20 Psoriasis Week in Mexico
- 2009/07/13 Psoriasis: The Naked Truth – The Search for Candidates
- 2009/07/10 Psoriasis Association of Slovenia on Psoriasis-international.org
- 2009/06/16 IFPA represented in workshop in the EADV Spring Symposium
- 2009/05/22 Psoriasis brought to discussion in the Portuguese Parliament
- 2009/05/07 Polish Psoriasis Association’s Activities
- 2009/04/27 Conference Debate "Pathogenic and Therapeutic Novelties"
- 2009/03/27 Acción Psoriasis submits a wide awareness project on psoriasis
- 2009/03/24 A strong support to European Dermatology Forum - Press Information by EUROPSO
- 2009/02/27 EUROPSO’s 2008 activities
- 2009/01/30 GIPSO at Namur Meeting of Patient Associations
- 2009/01/30 Congress for the 20 years of ASNPV onlus
- 2009/01/27 GIPSO at 1st Salon of Voluntary Work
- 2008/11/28 APLCP – Association Pour la Lutte Contre le Psoriasis
- 2008/11/20 World Psoriasis Day in Italy
- 2008/11/14 World Psoriasis Day in Germany
- 2008/11/14 Patient Guidelines on Psoriasis
- 2008/10/28 World Psoriasis Day Press Release from International Federation of Psoriasis Associations, IFPA
- 2008/10/22 Mexico greetings for World Day of Psoriasis
- 2008/10/21 A HOLISTIC APPROACH TO PSORIASIS IN GOSSELIES - BELGIUM
- 2008/09/15 Hug-Me Campaign, a story of success by Psoriasis Philippines (PsorPhil)
- 2008/09/09 Association Marocaine du Psoriasis (AMP) on Psoriasis-International.org!
- 2008/09/09 Spanish patients association, Acció Psoriasi, has joined Psoriasis International
- 2008/08/28 The Swiss Psoriasis and Vitiligo Association on Psoriasis-international.org
- 2008/08/07 Deutscher Psoriasis Bund e. V. now on Psoriasis-international.org !
- 2008/07/31 AEPSO Argentina
- 2008/07/11 Mexico patients association - AMCPSO joins Psoriasis International
- 2008/06/25 A.DI.PSO Italy is now member of the Psoriasis International network
- 2008/06/25 The Indonesian Psoriasis Care Foudantion joins Psoriasis International
- 2008/06/12 Psoriasis Association Malta on Psoriasis-international.org
- 2008/06/10 Psoriasis Australia Inc, a new partner association in the network Psoriasis International
- 2008/06/10 SPERANTA, the Romanian Psoriasis Patient Association joins the International Psoriasis Network
- 2008/05/26 PSOPortugal, new member of Psoriasis International
- 2008/05/09 GIPSO asbl becomes member of the Psoriasis International network
- 2008/05/09 The Dutch Psoriasis Patients Association (PVN) joins the network Psoriasis International
- 2008/04/30 PSO Austria subscribes to Psoriasis International
- 2008/04/25 Newest member registered on Psoriasis International - The Polish Psoriasis Association
- 2008/04/25 Psoriasis Philippines Online Community, Inc. is now connected to Psoriasis-international.org
- 2008/04/25 The Czech Psoriatic and Atopic Eczema Association joins the Psoriasis International network
- 2008/04/22 The Finnish Psoriasis Association joins the network Psoriasis International
- 2008/04/02 FEDIPSO onlus
- 2008/03/27 AEPSO Argentina, new member of Psoriasis International!
- 2008/03/04 The Psoriasis Selbsthilfe Arbeitsgemeinschaft e.V. (PSOAG) joins Psoriasis International
- 2008/01/14 The Colombian Psoriasis Foundation is now a member of Psoriasis International
- 2008/01/11 The Psoriasis and Psoriatic Arthritis Alliance joins Psoriasis International
- 2007/12/12 FEDIPSO, the Italian Federation of Psoriasis Patients’ Associations just joigned Psoriasis-international.org
- 2007/12/10 APLCP, the French Psoriasis Association of Patients, joins wwww.psoriasis-international.org
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Recent publications on Psoriasis and Atopic Dermatitis
on Psoriasis
IL-33 contributes to disease severity in Psoriasis-like models of mouse.
Duan Y et al.
IL-33 contributes to disease severity in Psoriasis-like models of mouse.
Cytokine.
2019 Jul , 119:159-167.
Immune cells infiltrating the psoriatic skin secrete high amounts of pro-inflammatory cytokines IL-17, TNF-α, IL-21 and IL-36 resulting in chronic inflammation. However, the exact cellular and molecular mechanisms have not been fully understood. We report here elevation of IL-33 expression in psoriatic lesions. Studies in imiquimod (IMQ)-induced mice with psoriatic inflammation confirmed a critical role for IL-33 in driving the disease. IL-33 reduces the CD4 and CD8 cells, inhibits autophagy (...)
see on pubmed
Association of plasma and urine metals levels with kidney function: A population-based cross-sectional study in China.
Chemosphere.
2019 Jul , 226:321-328.
Although environmental exposure to multiple metals is common, epidemiological studies on the associations of exposure to 23 metals with kidney function have not been analyzed. We aimed to investigate the associations of 23 metals levels with renal function.
see on pubmed
Models of human psoriasis: Zebrafish the newly appointed player.
Martínez-Navarro FJ et al.
Models of human psoriasis: Zebrafish the newly appointed player.
Dev. Comp. Immunol..
2019 Aug , 97:76-87.
Psoriasis is a human chronic, immune disease with severe cutaneous and systemic manifestations. Its prevalence, among the world population, highly varies with ethnicity and geography, but not sex from remarkable low levels in Asia to 2.3% in Spain, or an impressive 11.5% in Norway. The pathogenesis of psoriasis derives from complex genetic and environmental interactions, which creates aberrant crosstalk between keratinocytes and variated immune cell, resulting in open amplified inflammatory (...)
see on pubmed
on Atopic Dermatitis
What's new in atopic eczema? An analysis of systematic reviews published in 2016. Part 3: nomenclature and outcome assessment.
Clin. Exp. Dermatol..
2019 Jun , 44, (4):376-380.
This review forms part of a series of annual updates that summarize the evidence base for atopic eczema (AE). It presents the key findings from 11 systematic reviews published in 2016 that focus on AE outcome assessment, disease impact and nomenclature. Systematic reviews on the treatment and prevention of AE are summarized in Part 1 of this update, and systematic reviews on the epidemiology of and risk factors for AE are summarized in Part 2. Six reviews summarized what outcome measurement (...)
see on pubmed
Discovery of a class of highly potent Janus Kinase 1/2 (JAK1/2) inhibitors demonstrating effective cell-based blockade of IL-13 signaling.
Bioorg. Med. Chem. Lett..
2019 Jun 15, 29, (12):1522-1531.
Disruption of interleukin-13 (IL-13) signaling with large molecule antibody therapies has shown promise in diseases of allergic inflammation. Given that IL-13 recruits several members of the Janus Kinase family (JAK1, JAK2, and TYK2) to its receptor complex, JAK inhibition may offer an alternate small molecule approach to disrupting IL-13 signaling. Herein we demonstrate that JAK1 is likely the isoform most important to IL-13 signaling. Structure-based design was then used to improve the (...)
see on pubmed
Effect of cinnamamides on atopic dermatitis through regulation of IL-4 in CD4 cells.
Choi EJ et al.
Effect of cinnamamides on atopic dermatitis through regulation of IL-4 in CD4 cells.
J Enzyme Inhib Med Chem.
2019 Dec , 34, (1):613-619.
This study aimed to evaluate the effects of cinnamamides on atopic dermatitis (AD) and the mechanisms underlying these effects. To this end, the actions of two cinnamamides, (E)-3-(4-hydroxyphenyl)-N-phenylethyl acrylamide (NCT) and N-trans-coumaroyltyramine (NCPA), were determined on AD by orally administering them to mice. Oral administration of the cinnamamides ameliorated the increase in epidermal and dermal thickness as well as mast cell infiltration. Cinnamamides suppressed serum (...)
see on pubmed
